Pre-School and School-Age Irritability Predict Reward-Related Brain Function

4th June, 2018

8 June 2018, Newsletter

[Source: Medical X-Press]

Preschool irritability and concurrent irritability were uniquely associated with aberrant patterns of reward-related brain connectivity, highlighting the importance of developmental timing of irritability for brain function, finds a study published in the June 2018 issue of the Journal of the American Academy of Child and Adolescent Psychiatry(JAACAP).

“Irritability is one of the most frequent reasons for treatment referral and is present across multiple emotional and behavioral disorders,” said lead author Lea Dougherty, Ph.D., a clinical psychologist at the University of Maryland College Park. “Chronic irritability in school-age children and adolescents predicts depressive and anxiety disorders, suicidality, and functional impairment in adulthood. Despite its prevalence and central role in developmental psychopathology, the pathophysiology of irritability is largely unknown.

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