[Source: Medical News Today]

While one main risk gene may make an individual susceptible to autism or another neurodevelopmental disorder, it is the whole collection of associated changes in their DNA that decides whether they develop it and how severe it becomes.

This was the conclusion that researchers arrived at after analyzing developmental, cognitive, and genome sequencing data of hundreds of people with known risk genes together with that of their parents and siblings.

They suggest that their findings explain why two people carrying the same risk gene, also known as the “primary mutation,” can have very different symptoms of the associated neurodevelopmental disorder.

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